You start with Clapton with the Yardbirds, and the John Mayall "Beano" album w/Clapton, add the Gram Bond Organization Sounds of 65 w/Bruce and Baker. That brings you to this album.
The recordings are spread throughout the time of their first two studio albums, Fresh Cream and Disraeli Gears. There are songs never recorded on regular releases, live versions of songs from the regular releases, as well as early (different) live versions of songs on their later live releases on Wheels of Fire, Goodbye Cream and Live Cream, so there's no redundancy with previous releases.
Then you want to follow up on Bruce and Baker on their post-cream efforts. Clapton is, after all, only one third of the talent here. You already know about Blind Faith and Derek and the Dominos, right?
The sound quality suffers from 1966 studio engineers who don't yet know how to record a really loud band in the studio, or to recognize the bass as a lead instrument and not bury it in the background. As a result. the voices and instruments are too "cleanly" recorded, sucking out much of the fullness of the sound.
Picture these guys diving at their controls, turning all the knobs down to "1", while the Marshall amps are breaking the plaster out of the ceilings.
That said, the performances are brilliant! Who cares about the problems. It's not distortion or additional noise, but rather omission of what could have made it sound better than it does. If you want to get snobby about audiophile properties, you're missing the point. These are great performances we didn't have before, by brilliant artists, and they are supremely enjoyable for their musical value. I'm grateful to have them.