37 Downing Street is the compelling story of life "above the shop" in a small English town. During a time of uncertainty and changing attitudes 37 Downing Street chronicles a family's history from the last years of Queen Victoria's reign to 1930s Britain. Edwin and Mary meet by chance and fall in love in the summer of 1889 but neither could have foreseen the challenges ahead. Edwin is a bricklayer's labourer but he is ambitious and unwilling to follow the humble footsteps of this father. In search of well-paid work to support his bride-to-be he travels to the Isle of Wight but fate intervenes and he grasps the opportunity to learn a new trade with good prospects before returning to set himself up in Farnham as a high class fishmonger. As Edwin's business flourishes so he rises from a poor labourer's son to a respected and well-liked member of the community. To the townsfolk of Farnham, Edwin's large family seem to be enjoying life, but beneath the veneer of success things are not always as they might appear and the family endures many trials and tribulations over the years culminating in a challenge that threatens their future. Will Edwin have the strength to hold his family together as tragedy strikes?