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Autism, Brain, and Environment Hardcover – May 11 2006

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'The author covers the problems of recognition and diagnosis, genetic contributions, brain abnormalities, limbic dysfunction, physiological dysregulation, body and mind, biomedical therapy, and links with other disorders, as part of a detailed positioning of this arguments... The argument is concisely presented, extensively referenced and made easy to follow to its conclusion... Overall this is an important book, well argued and referenced. It should be read by all concerned with ASD.'- The Journal of The Royal Society for the Promotion of Health, JRSH'I would recommend this book to psychologists working in the field of ASD who want a clear and well argued introduction to a subject which, although undoubtedly controversial, deserves serious attention.'- Clinical Psychology Forum'Autism. Brain and Environment provides a new account of the biological basis for autism, with consequences for a wide range of professionals as well as for families.'- Psychology Teaching Review'I would recommend this book to psychologists working in the field of ASD who want a clear and well argued introduction to a subject which although undoubtedly controversial deserves serious attention.'- Dr. Bob Walley, Consultant Clinical Psychologist'This densely informative book is a comfort to read. One can browse or follow through. The index is enormous and useful. Definitions are strengthened. Gene and brain variations are covered and the nature/nurture interaction exposed.'- The Galton Institute Newsletter'This is a well- written user- friendly book. The key points at the end of the chapters give a helpful summary. The book presents a comprehensive overview of the aetiological factors in autistic disorders with extensive bibliography... Richard Lathe makes an excellent case for the interplay of factors and gives an unbiased presentation of the available evidence for all the possible hypotheses in the causation of autistic syndromes. The section on the impact of heavy metal toxicity is particularly interesting... This is an important book that brings together all the current issues in the aetiology of autistic disorders. The chapter on biomedical therapy, subtyping and interventions gives possible ways forward in management which may seem well worth adapting in clinical practise. This is a must- read book for trainees in psychiatry and paediatrics and for practitioners in the field.'- Journal of Intellectual Disability Research'Autism, Brain and Environment engages with wider scientific debate and is comprehensively researched.'- Journal of Biosocial Science

About the Author

Richard Lathe is director of Pieta Research, a biotechnology consultancy based in Edinburgh. He has extensive experience of academic and industrial research, his most recent area of interest has been in brain research and neuroscience, particularly focusing on the limbic system, autism and Alzheimer's. He has previously held professorship at the Universities of Edinburgh and Strasbourg. He is the author of over one hundred peer-reviewed journal articles.

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8 of 10 people found the following review helpful
Authoritative and Clearly Written Review of Autism Etiology April 28 2007
By Robert J. Krakow - Published on
Format: Hardcover
Richard Lathe has provided a comprehensive and well-written exposition of the science exploring the causes of autism. He thoughtfully describes the condition, explains how the evidence shows that there is a real increase in the incidence of autism over the past two decades, and gives persuasive evidence that the increase is most likely due to environmental factors, and is largely, although not completely, attributable to children's increased exposure to heavy metals.

Dr. Lathe expertly reviews the hypothesis that autism is primarily a heritable disorder. While acknowledging that genetic susceptibility plays a role in autism etiology - as it does in many diseases, Dr. Lathe shows why a genetic explanation alone is completely insufficient to account for the physiological mechanisms that cause most cases of autism the marked increase we have seen of autism among children.

Dr. Lathe also shows how the effect of environmental toxins on the limbic brain are the most plausible sources of explanation for the increase of autism and related disorders that exhibit similar symptoms.

Of special note is the fact that Dr. Lathe is a co-investigator if a recent study that has linked mercury toxicity to autism. In a study of children in a French clinic Lathe and others analyzed mercury and heavy metal toxicity through use of a technique called urinary porphyrin profiling analysis. This method, validated by more than twenty years of research and its use in detecting lead toxicity, is an accurate measure of heavy metal toxicity and body burden, and can determine mercury toxicity with specificity. The study showed that mercury toxicity was clearly associated with autism in the more than 200 French children who were the subject of the study.

Dr. Lathe's extraordinarily readable but still highly authoritative and exhaustively documented book is a valuable addition to the literature on the physiological causes and potential treatment of autism.

Robert J. Krakow
Comments about this book Nov. 2 2010
By Miguel Perez-Pouchoulen - Published on
Format: Hardcover Verified Purchase
Hi all,

I think this book is excellent. If you want to know the bases of autism and related factors this is the best way to do it. You can find a easy reading and follow the information that they mention to us. I really like this book and I think I did the best purchase, furthermore, this book is not expensive.