Well, I have played 130 hours so far, still 1 character, I have not progressed even 1/3 way through the main storyline and there is still a HUGE amount of side aspects to explore. I am saying this game is the ABSOLUTE greatest RPG game ever made..but some issues:
The lag does get so bad that it slows things to a crawls sometimes.
It crashes on auto-saves..so far 12 crashes (and I do think this is affecting my PS3 console since it now crashes on other games where it did not before)
The fun is endless, the quests and awards are unlimited...but to fix the above issues this is what you do:
(I have tested this over the last 23 hours of playing with a 100% success rate...so this does work)
Go into the settings, and un-check the auto-save features (3). You will need to start saving on your own more often of course, I even went back and checked the save on rest without any problems..so great, not only does it no longer crash at all...but the lag is ALL GONE...when I enter rooms or change environments (the usual loading points), it takes between 3-8 seconds only instead of 1 minute each time...so going store to store is a breeze.
My save game is 14mb, so very large...you can lower this by waiting for a total of 30 days (in a row), this will clear the entire game of dead corpses and re-spawn enemies that should be re-spawned. This will significantly lower the save size but I have not needed to do this since I no longer have any issues...
We'll see what future patches will resolve, and yes there are issues (quests being unable to be completed, quest items not leaving your inventory etc...but these are all superficial).
Hope this helps :-)
UPDATE Jan 6 2012
- Now have played over 200 hours, had 3 crashes only since I applied my tricks, still better than crashing every time I play. You get used to saving on your own, and this overall makes the game play much faster as well