The series is a takeoff of National Lampoon's Animal House and Van Wilder focusing on the football-centric university, Blue Mountain State, and its rather awkward team "The Goats." It covers topics of college life, including football, scoring with women, drinking binges, wild partying, and hazing.
* Alex Moran (Darin Brooks): A freshman second-string quarterback for the Blue Mountain State team and the first 10,000 yard passer in Wyoming high school history. Unlike the rest of the characters, Alex does not see college football as a stepping stone for the NFL and is content to spend his days as a back-up player and a life as an "Average Joe" once he graduates college. Instead, he is dedicated to having as much fun as humanly possible while in college, which includes getting drunk and having sex. He is from Cheyenne, Wyoming.
* Sammy Cacciatore (Chris Romano): The team mascot (Mounty, The Mountain Goat Mascot) and Alex's roommate. Is constantly searching for girls and excuses to get drunk, with his drinking often leading him into misadventure. Like Alex, he grew up in Wyoming.
* Thad Castle (Alan Ritchson): A junior linebacker/team captain from Connecticut. Despite his status as a two time consensus All-American and team record holder for most tackles in a game (a game which he was subsequently ejected from for calling referees "butt faces"), Thad is largely hated by his teammates for his bullying and high strung antics when things do not go his way. Has a father who died while in the military, stationed in Bosnia and has an attractive half-sister of which he is overly protective. He is also heavily prone to engage in excessive homoerotic behavior, especially in the hazing rituals of freshman players. He also uses rabies to enhance his performance from time to time, as he stated in episode "Legend of the Golden Arm," when saying that "only idiots" use steroids because rabies is undetectable for current doping test methods.
* Craig Shilo (Sam Jones III) (Starring Season 1) : Last years National High School Player of the Year, Craig Shilo is the team's star freshman player. Unlike his teammates, Craig is rather straight-laced and committed to his ultra-manipulative girlfriend Denise, with whom he breaks up when he finds out she cheated on him with other men, including a man from her marketing class whom she tells Craig is an NFL scout. Shilo is from Columbus, Ohio.
* Coach Marty Daniels (Ed Marinaro): Six time National Champion, and long standing pillar of the BMS community, Coach Marty Daniels is the winningest football coach in Blue Mountain State history. Coach Daniels has accumulated 243 wins over the years and expects to add to that total this year in his quest to break Joe Paternos record.
* Denise Roy (Gabrielle Dennis): Denise is Craig Shilo's high school girlfriend. A former homecoming queen and star student at Blue Mountain State, Denise is a cold and calculating figure who withholds sex from Craig to make him play better, all the while sleeping around behind his back (having three-ways with two other women and sleeping with a guy from her marketing class). She is often at odds with Alex Moran, who sees through her facade.
* Larry (Omari Newton): A junior defensive back, who plays a "sidekick" role to Thad. Although the event is unspecified, it is known that Larry once helped Thad out of a tough situation.
* Donny (Rob Ramsay): An offensive lineman of an unspecified year.
* Harmon Tedesco (James Cade): The kicker for the football team. While living the life of a Special Teams player at BMS, Harmon has a great deal of experience with drug use such as Marijuana, Ecstasy, Cocaine and Heroin.
Metacritic gave the series 38 out of 100, from the 4 reviews it collected, and a user score of 8.7 out of 10 based on 32 votes. Brian Lowry of Variety found that "Blue Mountain embraces that (crude comedy) aspect of Spike's mandate over all else -- putting the bodily function/semi-nudity cart before the sitcom horse." Lowry also stated that, "(Spike) has simply made this too-blue "Mountain" into a comedic molehill." Mark A. Perigard of the Boston Herald gave the series a favourable review saying, "Blue is also frequently funny in a raunchy American Pie way. Its a college comedy in which the guys want to get wasted and laid, in whatever order." As to production Perigard described it as "solidly made on a cable budget." Joe Walljasper of the Columbia Daily Tribune describes the series as appealing to those who viewed the film Porky's and "felt that the jokes were a little too high-brow."
The show has averaged 949,000 viewers through its first six episodes while improving on the time slot by 165% among men 18-24. As a result, it has been renewed for a second season.