Possession begins with the myth of a young woman who bethrothed herself to the Atrox, Ursula, whose famous beauty was so reknowned all who looked at her felt blessed. But her unlucky fate was already decided at birth, when she was born clutching a jewel in her fist. Her peasant father rushed to the castle to get a priest, and when they returned, the jewel had vanished. Such was her fate; "all good would slip through her fingers". In the present day, Serena Killingsworth, a Daughter of the Moon, is struggling with her life. Stanton, the guy she once loved (and still loves, though she won't admit it to herself) has betrayed her by becoming the Prince of Night. Her heartache is so heavy it is like a constant stone crushing her chest. She hasn't been sleeping or eating well... She dreams about Stanton visiting her at night, and though her line of clocks on her dresser is unmoved, these night visits still unnerve her. In the beginning, she is racing through the post-school crowd, she escapes the guy who is crushed on her, Mr. Wrong (Jerome) by cutting through an alleyway. There, she accidentally bumps (more like smashes) into an elderly woman. Serena is knocked to the ground. The woman uncaps a bottle and forces a strange brew into Serena's mouth. Serena blacks out and when she wakes up, it's nighttime. Soon she starts having nightmares, strange thoughts, and starts acting like a completely different person some of the time. It's frightening her, and her friends. What's going on with Serena and who was that woman!?