Ticket to Ride (TtR) base games come in two flavours: this one covering Europe, and the North American map (reviewed elsewhere). The gameplay in both is almost identical (there are a few tweaks to the rules with the Europe expansion, but nothing major), the cards a bit bigger in Europe compared to the original North American release, and of course the map is different.
It's the different map that will entice most players. If you live in Europe, it's nice to play on your home turf. If you are used to the North American map, then the Europe map gives you a different playfield to enjoy. The two maps (Europe and North America) play quite differently, each has its strengths and weaknesses, and both can be fun. I tend to play both about equally, switching between them at times simply to shake up the game a bit and prevent settling into the same strategies each time.
If you play TtR already, Europe is a great new map. If you don't play TtR, you can easily choose either base game and you won't go wrong. Excellent game!