"There's plenty to think about and discuss in this diary-format novel based on the notorious case of Mary Mallon, also known as "Typhoid Mary." It's 1906 and 16-year-old Prudence is in her final year at a school for girls... but, unlike most of her classmates, Prudence isn't interested in being an ornamental "Gibson Girl." Instead, she craves a job where she can actually make a difference. She's always been scientifically curious, particularly regarding the nature of infection and disease.... When she lands a position as assistant to an epidemiologist working for the Department of Health and Sanitation, she quits school completely to help investigate the microbial mystery of Mary Mallon, an immigrant cook and suspected "healthy carrier" of typhus, who adamantly denies she's been unwittingly infecting a series of employers' families and instead insists she's the victim of anti-Irish discrimination. A deeply personal coming-of-age story set in an era of tumultuous social change, this is top-notch historical fiction that highlights the struggle between rational science and popular opinion as shaped by a sensational, reactionary press."