** Update: I'm almost done with the game now, and I must admit that it seems more like a budget title. They definitely didn't put as much into this one as they did into the second game. The cities all seem smaller, and have a lot less to destroy. The enemies are absurdly repetitive (yes, much more so than before if you can believe it), and the new weapons aren't as exciting as the now missing meteor shower. I thought there would be a lot more to this game, but all I have left is collecting energy cells and I feel like I've barely done anything. This would be a great game for $30, but at $50 it's verging on being a rip-off. Just wait until the price goes down, because they will have to lower it if they want to sell a lot of copies.**
If you're already a Destroy All Humans fan hoping for the next fix, this is definitely it. If you're new to it, this is a great place to start. The plot, subplot, and characters are all pretty absurd as usual. The humor is more crude than ever, and the excessive violence comes in even more varieties. The AI (people) are stupid as ever, and still blurt out all kinds of funny one-liners. The music is all right, and the graphics are pretty nice for the most part, except for all of the humans which are blocky as usual.
You complete missions toward a greater objective, as well as self contained odd jobs. You have a nice array of weapons and "pyschokenetic" abilities, as well as a flying saucer and the new giant metal robot fast-food chain mascot that shoots lasers out of its eyes and vomits corrosive acid. When you're not completing a mission or odd job, you can just have fun wreaking havoc however you want, which might be the best part of the game.
The controls are fairly awkward at first, but well worth learning. Crypto, his saucer, and Big Willy all control differently. Crypto uses the control stick and pointer, and you aim his weapons by pointing at the screen. The saucer and Big Willy use the gyroscopic motion sensor in the remote, which takes getting used to. Big Willy is a cool edition to the game and more than just a gimmick. Ultimately, it shouldn't take you too long to get the controls down and when you do, you'll see how easy and convenient they really are.