Drug-Induced Valvular Heart Disease [Paperback]

Steven Droogmans (Author)

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Product Details

Paperback: 52 pages
Publisher: Nova Biomedical Books; 1 edition (April 2011)
Language: English
ISBN-10: 1616689781
ISBN-13: 978-1616689780
Product Dimensions: 21.1 x 13.5 x 0.8 cm
Shipping Weight: 45 g

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Product Description

The notion that drugs can induce valvular heart disease (VHD) has occurred since the sixties and has received a lot of attention in recent years. Overstimulation of the serotonin 2B receptor (5-HT2B) leads to valvular fibroblast proliferation and thickening of the valvular leaflets with reduced mobility and regurgitation as a consequence. This book focuses on different aspects of this distinct kind of valvulopathy including pathophysiology of drug-induced VHD, histopathological and echocardiographic characteristics, drugs associated with VHD, the influence of cumulative drug dose and risk factors and others.