We loved the book by Michael Palmer, on which this movie is "officially" based - but except for experimentation on unknowing human subjects, the two stories bear little more similarity than Palmer's name as "author". Nonetheless, Hugh Grant as Dr. Guy Luthran does a quite competent job in a serious part that's a departure from his normal romantic comedies. Gene Hackman also stars as the "evil" doctor who it turns out is doing illegal surgeries on homeless subjects who get "selected" by special ID work at the hospital where our hero works. A missing victim soon sends Luthran on a scary search for homeless people deep in the city's subway bowels, where David Morse ("Hack", et al) is stalking him for some unknown "FBI" reasons. Sara Jessica Parker serves as a supporting mild love interest but shows up later as part of the insidious plot. Some ethical issues near the end of the film raise some interesting points to ponder, and leave us guessing 'til the end which way things might go.
A decent plot, good acting, and sustained suspense, with some credible acting by all the name actors, add up to an entertaining movie. The DVD itself has no extra features and comes in a cheap cardboard "keepbox", with only Dolby Surround Sound, not 5.1 Digital. Aside from these quibbles, an enjoyable hour-and-a-half awaits!