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Genetic Disorders among Arab Populations
 
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Genetic Disorders among Arab Populations [Hardcover]

Ahmad S. Teebi (Editor), T. I. Farag (Editor)

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Genetic Disorders Among Arab Populations Genetic Disorders Among Arab Populations
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"The Arab populations...provide a genetic gold mine, as it were, awaiting exploitation. This book shows how successful that exploitation has been so far.... The book is well produced...and the case illustrations...are sufficiently informative. Apart from its intrinsic academic interest it is bound to be useful to physicians and medical students in the Arab countries, but will also be valuable for reference for those clinicians in Britain and Europe who see patients from the Arab world..."--Journal of Medical Genetics

"The first comprehensive book on genetic disorders in the Arab population....A clear and succint discussion of Islamic laws pertaining to reproductive issues of family planning, abortion, artificial insemination, donated sperm, and in vitro fertilization....Wealth of information that makes it very useful for health care professionals in Arab countries. The authors and editors should be commended for a comprehensive and clearly written volume."--Annals of Saudi Medicine

**"This book dedicated to 'The whole Arab family', is definately of great interest to medical geneticists and related specialists of the whole world."-- Noted from journal published by KARGER (not on review)

Product Description

Few regions of the world have a more varied physiography or a richer ethnic, religious, social, and cultural mix than the Arab world. As a consequence, Arabs are genetically diverse despite their linguistic and religious cohesion. High but variable rates of inbreeding prevail in all Arab countries with numerous examples of isolates among them. These include some Bedouin groups, Nubians, Druze, Jews, and others. Arab populations have high frequencies of autosomal recessive disorders, homozygosity of autosomal dominant and X-linked traits, and a wealth of new syndromes and variants, the majority of which are autosomal recessive. Genetic disorders that cause major health problems include hemoglobinopathies, neurogenetic disorders, inherited metabolic diseases, and inborn error of morphogenesis. Because of their characteristically high prevalence, some of these disorders are considered markers for Arab populations. This book presents the unique profile of genetic disorders and variants in Arabs. In addition, it describes their unusual demographic pattern including fertility rates and other population dimensions, family structure, magnitude and effects of consanguineous marriages and indicators of health and disease. Genetic counseling and the distinctive cultural and religious attitudes towards various genetic issues are also presented. Disorders that have increased tribal occurrences or are limited to large kindreds, as well as small geographic or religious isolates, are highlighted to facilitate their recognition, study, and management.
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