This is my first and only experience with a graphics tablet EVER, that said, I am very happy with it (I've only had it for three days).
The first thing that struck me is how thin the unit was, (about an eighth of an inch in the front, and maybe a half inch in the back. It is pretty light, yet not at all flimsy. I found the drawing area to be larger than I had expected, and since the drawing surface represents your entire screen I think a much larger area would make it awkward when using it as a mouse (meaning, to go from the upper corner to the bottom of the screen, you have to do the same on the drawing area.) This is just how all pads work when using them as your mouse.
And speaking of the mouse, at least one reviewer had called the included mouse "useless" and I mostly agree. While the mouse works okay, it must be used on the surface of the pad, and it's a little frictiony (is that a word?) when you slide it around, which made me worry about unnecessary wear to the drawing surface. Really, if you already have a good optical mouse that you're comfortable with, you will want to skip the included mouse altogether.
I used the pad with "The Gimp ver 2.2" which is an open-source graphics program (i.e: FREE!) and it worked seamlessly with the Genius MousePen Tablet- Like they were made for each other! It came budled with Adobe CS3 Extended, and Corel Painter X (Trial versions) I have yet to check out, but it's nice they are included.
All of the buttons along the top of the pad (new, open, save, print, exit, cut, copy, paste, undo, back, forward, e-mail, and www) worked perfectly with no set up whatsoever. I was pleased when the "www" button launched my browser with a tap of the pen.
One little tip, you'll want to keep the pen mostly straight up and down when you are drawing, as the tip is pressure-sensetive and works badly if you slant it too much. HAVE FUN!!