Hemochromatosis: Genetics, Pathophysiology, Diagnosis and Treatment [Hardcover]

James C. Barton (Editor), Corwin Q. Edwards (Editor)

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Product Details

Hardcover: 616 pages
Publisher: Cambridge University Press; 1 edition (Feb 28 2000)
Language: English
ISBN-10: 0521593808
ISBN-13: 978-0521593809
Product Dimensions: 27.6 x 22.4 x 4.6 cm
Shipping Weight: 2.5 Kg
Amazon Bestsellers Rank: #1,978,126 in Books (See Top 100 in Books)

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Review

"This is the best, most comprehensive review of hemochromatosis and iron metabolism that I have ever encountered. It will become a required reference for anyone treating or researching this disease...4 Stars!" Doody's Review Service ®

"Barton and Edwards have assembled experts from around the world to write highly authoritative articles about all aspects of hemochromatosis. Molecular genetics, genetic epidemiology, pathophysiology, clinical management, and screening are the main topics. Ethical and social issues related to hemochromatosis are also considered. Throughout this book, the reader can feel the excitement sparked by the discovery of the hemochomatosis (HFE) gene. This book is particularly strong in its coverage of clinical genetics...written by ninety-three diverse authors...a tight collection of compelling and informative chapters, each one contributing to the cogency of the overall discussion." The New England Journal of Medicine

"James Barton and Corwin Edwards are two American physicians with enormous clinical experience in hemochromatosis who have brought together 100 of the world's experts on iron overload to create a major monograph about hemochromatosis that will dominate the field for years to come. Their book, Hemochromatosis, is clearly written, evenly edited, and well made. It is also timely because it is the only monograph available in a field that is rapidly expanding...This skillful organization of knowledge into a highly readable monograph is a pleasure to use." The Permanente Journal

"It is a pleasure to find in a rapidly expanding field of knowledge a monograph so well written, edited, and constructed. The skillful organization of knowledge is an exciting thing to see...All medical libraries will want this book, to my knowledge the third monograph on the subject ever published in English and the first in the past four decades. Many physicians will find the price acceptable when they realize that a dozen undiagnosed patients lie waiting in the average practice." Journal of the American Medical Association

"...it provides a wealth of information....an excellent source..." Susan Hollan, Budapest, Hungary

"This is an authoritative book on hemochromatosis." Oncology

"A remarkable resource of information about haemochromatosis...a valuable resource for researchers interested in haemochromatosis." Human Genetics

"Excellent." Journal of Gastroeuterology

Book Description

Once considered a rare condition, hemochromatosis is now acknowledged as one of the commonest inherited disorders, affecting one in two hundred people of Western Caucasian descent and in the U.S. alone, over one million people. This is the most comprehensive clinical reference yet on hemochromatosis. The international team of 94 authors from twelve countries includes specialists in internal medicine, hematology, hepatology, genetics, biochemistry, and molecular biology. In 57 in-depth chapters they cover all aspects of pathophysiology, epidemiology, diagnosis and treatment. The text thoroughly explains the latest developments in the genetics of the disorder, including sections on screening, diagnostic techniques, and clinical complications. In addition, chapters consider social and ethical issues. With over 200 illustrations--including 40 color plates--this is today's definitive resource for all clinicians involved in the management of hemochromatosis, and for scientists interested in iron metabolism and iron overload.

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First Sentence
In 1847, Virchow reported the occurrence of golden brown granular pigment in sites of hemorrhage and congestion; this pigment was soluble in sulfuric acid, yielded a red ash on ignition, and then produced a Prussian blue reaction. Read the first page

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