Even though this is only the first volume of a two part series, I'm sure that Karas is going to be one of the best, if not the best, anime of 2006. It has everything that all good anime have, including excellent animation, both 2D and 3D, which is blended in Karas so perfectly it's difficult to tell difference between the two; the music is good as well, with emotional tracks that highlight the intense, non-stop action; and of course their is the excellent voice-acting on both the English and Japanese tracks. The only thing I was unsure of was the story, that's because it wasn't yet finished.
From what I gained, though, it follows a Karas, a warrior capable of entering both the spiritual and physical world to do battle, who is thrust into a battle with a former Karas known as Eko, a man who is meddling in the two worlds of existence in Tokyo. Spirits are growing sick and humans are dying left and right. To make matters worse, monstrous, robotic demons known as Mikura are prowling the streets and Karas must put a stop to them in order to save the humans who are the Mikuras' food source.
Karas is somewhat of a cross between Blood (for it's dark settings), Vampire Hunter D: Bloodlust (for the crisp animation), and Kakurenbo (for the elements of horror). So for fans of the mentioned anime, this will definitely be an anime for you. What am I saying... Karas is an anime that really shouldn't be missed if you consider yourself a fan of anime. It has the power to stand right alongside Akira, Ninja Scroll, and Ghost in the Shell as anime's classics.
A quick note on the DVD: It's very cheap, as in inexpensive, yet it's loaded with special features, including a mini-comic book (not manga) with a special Karas adventure. You don't expect a DVD to have this much for so little, which only adds to the appeal of Karas.