I installed this on both my laptop and my daughter's, and was surprised in both cases at how rough the product was. I know Kaspersky is a big name, so I was expecting everything to go without a hitch. Both machines were running Windows 7 Ultimate.
On both computers, the installer autoran when I inserted the disk. And, in both cases, it told me that I didn't have sufficient privileges to complete the installation, even though I was logged in as an administrator. I had to exit the installer, open the disk in Windows Explorer, and manually "Run as Administrator" to get it to work.
Both of the machines were running Microsoft Security Essentials, which the installer detected, and offered to uninstall automatically. It failed to actually do so on my computer, and I wound up having to uninstall MSE manually. It did, however, work on my daughter's computer. In both cases, it then required a reboot to continue the installation.
I had selected the option to download the latest version. Surprisingly, this did not also download the latest definition file, but instead brought down one that was several days old. If I hadn't accidentally clicked on the "update" button on one of the computers, I wouldn't have noticed this detail.
As soon as I had it all installed and updated, I ran scans on both computes. When I came back half an hour later to check on them, I discovered that my daughter's computer had shut off. While MSE will keep a laptop from going to sleep while it's in the middle of a scan, Kaspersky apparently isn't that sophisticated. If your power plan puts your computer to sleep, you have to manually change it or put your computer into presentation mode to allow the scan to finish.
Kaspersky didn't find anything on either computer, so I can't speak to its friendliness in dealing with malware. If I do suffer an infection, I hope the removal procedure is more polished than what I've seen so far.