First of all, I feel I should state that I am a huge fan of B-movies, cult movies, bad cheesy old horror/sci-fi movies, anything weird etc, and if you are not into this kind of thing, this movie probably isn't even worth one star to you. That being said, I highly recommend this movie to anyone who can relate to my obsession.
Mesa of Lost Women is often compared to the movies of director Ed Wood, and is considered by some to be the "worst movie of all time," but I don't think that analysis of the film is entirely fair or accurate. Don't get me wrong, I think Ed Wood was a genius when it comes to schlock, and comparing any B-movie to one of Wood's films should be considered the highest possible compliment, but this movie differs from Wood's movies and just about any other grade Z film I can think of, and is certainly not the worst movie ever. (It sure as hell beats watching Gone With the Wind!)
First of all, as soon as this film begins, it is plain to see that this is movie is not meant to be taken as a serious straightforward attempt at horror/sci-fi. The bizarreness of this movie is deliberate, effective and very unusual for its time. If this film was made by David Lynch or John Waters, people would be calling it the eccentric work of a genius, but since it was made in 1952 when people just didn't make those kind of movies, most people mistake it for an inept attempt at making a "normal" monster movie. In fact Mesa of Lost Women resembles the work of Lynch at least as much if not more than it does the movies of Ed Wood, and although Mesa of Lost Women has been accused of "making no sense," It actually makes a hell of a lot more sense than Mulholland Drive, and is just as understandable and enjoyable as Eraserhead which, in my opinion, is Lynch's best movie.
The soundtrack of the movie also deserves to be mentioned (way cool and also very unusual for its time.) Jackie Coogan is great as a deadpan mad scientist and Harmon Stevens is excellent as the crazy Dr. Masterson. Watch for his odd frozen facial expressions. This is a must-have for b-movie fans or anyone who appreciates weirdness on film.