I'll start by saying that this anime is too long. There are way too many episodes in this series. I know what you're thinking. Thirteen is the absolute lowest an anime can go without becoming an OVA. And that's exactly my point. The last few episodes is where the gold is in this anime, and really a lot of the episodes never followed any real story line. This would have been a great OVA, had they done some episode editing.
Case in point, the first episode is about ghosts (with another episode later on also being about a ghost), the second is about aliens, the third about biological disasters, another episode deals with androids, and another with virtual reality. Though it all follows in line with the concept of the anime, it doesn't progress the story line in any way. In fact, two of the episodes, the last two on the first disc, goes back to the much more dangerous and adult Mezzo Forte in the form of flashbacks. You'd think this a good thing, but the obvious difference between the two makes the Mezzo series look terrible beside its prologue, Mezzo Forte. The animation quality in Mezzo Forte was just too good.
That's not to say that this anime was all bad. The characters, for one, are hilarious. Mikura is the gunslinger/beautiful-chick that is common in this genre who gets a certain amount of pleasure out of the violence she dishes out. Kurokawa is an ex-cop who knows the darker side of his former job, and who also loves to eat noodles, and Harada is the brains of the bunch, who seems to have a crush on Mikura that never comes through in the story. Also, there are the weird Black Scissors, a gang of assassins and underworld thugs; little Asami, the protege; a mysterious assassin that was seemingly hired to kill Kurokawa, but by who?; and a cat-faced police chief who supplies the DSA with their ammunition.
The story also isn't that bad, when it finally kicks in. Without spoiling much, the last five episodes involves a look into the underworld as well as a peak into the world of crooked cops. The story itself is driven by action packed scenes--gun fights, fist fights, explosions, car chases, and the like--along with a lot of comedy, even when it starts to get serious. The common theme in every episode, however, is that the DSA (Danger Service Agency) will accept any dangerous job given them, for a price.
I can't recommend this anime for the casual fan. Even the value of the box set wouldn't make it worth someone who has only watched the anime on Adult Swim. I also can't recommend it to anyone who enjoyed Mezzo Forte, as the face-lift this series had to go through to make it more "watch-able" seems to alienate it from its much more violent and sex-filled prologue. However, if you enjoyed the cut version of Forte, and you're curious about the characters left behind, then I can recommend this. I can also recommend this for anyone who like solid action with little nonsense.