One of the funniest films ever made that still manages to hold up an engaging plot. A total winner.
It features some of the most genuinely stupid and amusing tough guys in the history of cinema, and a tantalizing slow burn by Deniro, a shortchanged ex-cop, who just wants a peaceful little coffee shop as payment for his decency and integrity. The comic chemistry between Robert De Niro and Charles Grodin is top-drawer. Surrounded on all side by ethical infants, these two characters at least know the difference between virtue and vice, and are ironically the moral backbone of the film.
Comedies that don't wallow in their humor are twice as much fun, and Midnight Run maintains a swift pace throughout. Situation-wise, it's a dynamo of action. I found the denouement to be quite moving as well, at the very least it provokes thought.
If you're looking for a comedy with depth, bite, wit and excitement, then catch Midnight Run. The DVD's spiffy special features quite simply reinforce my recommendation of purchasing this one, not just renting.