What a great premise for a modern horror story: Young Frankensteins bent crossing the line between life and death. It is a creative and interesting premise along the lines of so many classics, including, of course, Frankenstein, The Fly (the re-make, especially), and The Man With the X-Ray Eyes. Of course, there will be hell to pay for "going where Man ought not go." Oh yes, there'll be hell!
But where the movie fails is in its rather silly, preachy lecture on the consequences of these actions. I won't give it away here, but the film turns into a cheap spin on a familiar ghost story, something done to much better effect in The Sixth Sense. The acting is just average, with Julia Roberts looking better than average, and constraining her hideous laugh, but the rest just mailing it in--with one exception. Kevin Bacon. He has turned out to be a terrific actor all around (including in Mystic River), and he is a real stand out in this film, too. Too bad he isn't enough to save it.
Watch this movie for the premise, for the director's ability to create suspense, and try not to cringe too much as the truth is revealed. Once again, a great premise dies because of bad execution.