The New Horizons mission is the first spacecraft to reconnoitre the Pluto-Charon System and the Kuiper belt. This pioneering mission explores the outer edge of the solar system, arguably the last frontier of planetary exploration. This book describes the mission, its objectives, expected results, payload and data products in articles written by the scientists and engineers most closely involved. This mission has the potential of revolutionizing our understanding of the formation of the solar system. It is of interest to all research scientists, graduate students, and educated laymen who are interested in the exploration of the solar system.