I'm a huge DM fan, so that will probably colour my review despite my best efforts to be impartial. 5/5 is my rating of the CD relative to majority of 2005 CDs, compared to other DM CDs, I'll give it a 3.5/5. It's definitely not as strong as Violator or Songs of Faith and Devotion, but it's probably on par with Ultra and Black Celebration.
Thematically, it's similar to SOFAD with a mixture of religious and secular themes, largely focusing on dismal themes. The line "Pain and Suffering in Various Tempos" on the back of the CD describes it quite well. It is probably the darkest of the DM CDs.
Musically, it tends to favor the more dissonant style of DM songs. If you liked, "I Feel You", "Barrel of a Gun" and "Useless" you'll probably enjoy this CD. With the exception of "Precious", by far the strongest track, there really isn't a song that has a strong melody. This is really my biggest complaint with Playing the Angel. Most of the tracks, in particular those penned by Gahan, rely on the base line to carry the song, unfortunately this applies to the ballads as well, which don't match other DM ballads like "Judas", "Home" or "Question of Lust". The more up tempo tracks, like "A Pain that I'm Used to", "John the Revelator" and "Suffer Well" are pretty solid, and with the exception of "Damaged People", which sounds alot like a song from Jesus Christ Superstar, and the instrumental "Introspectre" there aren't any real misses.
This is a CD that sounds better the more times you listen to it, so you should probably bear that in mind and try to hear the songs a couple of times before making a decision about it.