I hesitated buying this as I saw the one and only review was bad, but went against my better judgement and ordered it anyway. I installed the card, booted my PC (Vista 64-bit), and Vista loaded drivers for it. I plugged in my firewire device and nothing happened (Windows didn't detect it, and my device did not seem to detect it was plugged in). The flyer that came with the card says to install the drivers even if Windows installs a native driver, so I ran the installation from the included CD. Halfway through the installation, my PC crashed (blue screen). When it rebooted, it blue screened again before going into Windows. I rebooted again, and booted from Last Known Good config, and my PC is okay again. I am returning this card as it does not appear to work with my PC.
Long story short, if you can get it to work with your PC, who knows -- it may be a great card. However, it doesn't work on mine, and apparently on one other person's, either. So, one star. Both the description on Amazon and the included documentation state it is compatible with 64-bit Vista, but apparently not on mine.