This omnibus collects Remender's complete Punisher run in one book:
Punisher (2009 8th Series) #1-16
Punisher (2009 8th Series) Annual #1
Dark Reign The List Punisher (2009) #1
Franken-Castle (2010 Marvel) #17-21
Dark Wolverine (2009)#88-89
Punisher In the Blood (2010 Marvel)#1-5.
Coming from a Garth Ennis AND a Rick Remender fan, I will say that this is an outstanding book. Let it first be pointed out that this is a VERY different take on the Punisher, especially in comparison to Ennis' long run. I could see many hardcore Ennis fans having a hard time dealing with a lot of the subject matter, which ranges from monsters to Frakenstein versions of Frank Castle to the use of magic. However, I think that going into this with an open mind will give most readers a thoroughly enjoyable reading experience.
The first two arcs with Opena and Huat on art are fantastic, and represent a complete story (with a stunning WOW factor at the end of issue 10 that I won't go into). Following that, we see the Frankencastle story arc, which was surprisingly amazing. The last story arc features Frank back in human form, and is a solid closure to the series.
The only negative aspect of the book (hence the 4.5 stars, not 5), is due to the four-issue Dark Wolverine/Frankencastle crossover with Remender, Daniel Way, and Marjorie Liu. Any time that you have multiple writers alternate storytelling/scripting, it's a near guarantee that it's not going to be that great. But if you can get past that little hiccup, the rest of the book is phenomenal. As an aside: what was Marvel thinking with Daken? I'd never really read anything about him before this, but I find him to be a completely unoriginal and boring character.
On the whole, Remender incorporates clever story-telling and a surefire knowledge of Marvel lore and old characters to make this a rich and fulfilling run. He includes many long lost characters from the 70's and 80's that I would have glanced over and turns them into fun, interesting, and strangely disturbing villains. Frank Castle is still the ruthless, hardcore killer that we know, and there are many "oh my god did that just happen" moments along the way.
The part of the story I was most worried about was the Frankencastle arc. It seemed a very strange thing to feature in a Punisher comic. But I went into it with an open mind and actually discovered the Frankencastle story arc with Tony Moore on art to be one of the best of the entire book (discounting the Dark Wolverine crossover part of the arc - serious, skip it).
If you are an Uncanny X-Force fan, I would highly recommend this. I feel that this is the defining run where we see Rick Remender transform from a "pretty good" writer to simply "fantastic."