I am a big fan of the original games and personally thought the live-action ones were very poorly done. RE: Degeneration is much better than those but for those with high expectations it will fall short.
In terms of CGI the movie is good to look at. It reminds me of the cut scenes in the games, which is a good thing. The characters, despite being based on Claire and Leon, look very different from the original. According to the inteviews with the producers they tried to make the movie accommodating for non-gamers too, but I wouldn't imagine someone who haven't played Resident Evil to be satisfied after watching this.
Fans will probably enjoy the movie with two of the most popular characters in the RE franchise making a comeback. The movie overall has a sleek design, quite comparable to FF: Advent Children. It also has some hilarious special features which are actually worth watching. But if Resident Evil is a relatively new concept to you or if you don't enjoy watching zombie movies without gore (yes, bizarre) this might not be something you'd want to spend your money on.