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Signal Transduction in Leukocytes: G Protein-Related and Other Pathways [Hardcover]

Pramod M. Lad , John S. Kaptein , Ching-Kow Lin

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Book Description

Nov. 27 1995 0849366941 978-0849366949 1
Signal Transduction in Leukocytes presents important principles and various aspects of cellular regulation in leukocytes. The book discusses receptor structure and signaling, emphasizing cytokine receptors and the T cell and B cell antigen receptors. It investigates the role of the heterotrimeric G proteins and small G proteins as transducers.
Authorities in each field cover a wide range of topics. They explore propagation of signaling cascades through second messengers and serine/threonine kinases, the initiation of signaling from the B and T cell antigen receptors by tyrosine phosphorylation and protein recruitment, and the role of signaling in cell-cell interactions and the regulation of the cell cycle. The book outlines the relationship of receptor signaling to inflammatory reactions of neutrophils, eosinophils, and macrophages.

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The term "signal transduction" denotes the biochemical sequence of reactions that occurs as a cell responds to external stimuli. Read the first page
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Front Cover | Copyright | Table of Contents | Excerpt | Index | Back Cover
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