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Structural Bioinformatics [Paperback]

Helge Weissig , Philip E. Bourne
5.0 out of 5 stars  See all reviews (3 customer reviews)
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Book Description

Feb. 7 2003 0471201995 978-0471201991 1
From the Foreword
"[A] must read for all of us committed to understanding the interplay of structure and function...[T]he individual chapters outline the suite of major basic life science questions such as the status of efforts to predict protein structure and how proteins carry out cellular functions, and also the applied life science questions such as how structural bioinformatics can improve health care through accelerating drug discovery."

This book provides a basic understanding of the theories, associated algorithms, resources, and tools used in structural bioinformatics. The reader emerges with the ability to make effective use of protein, DNA, RNA, carbohydrate, and complex structures to better understand biological function. Moreover, it draws a clear connection between structural studies and the rational design of new therapies.


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Review

"This book is a gold mine of fundamental and practical information in an area not previously well represented in book form.” (Biochemistry and Molecular Education, September/October 2003)

"...a gold mine of fundamental and practical information.... This book is destined to become a classic reference work for workers at all levels in structural bioinformatics...recommended with great enthusiasm for educators, researchers, and graduate students." (BAMBED, Vol. 31, No. 5, 2003)

"...recommended for anyone who wishes to develop bioinformatics tools for protein structure analysis." (The Biotech Journal, April/May 2003)

"...a useful and timely summary of a rapidly expanding field." (Nature Structural Biology, Vol. 10, No. 8, August 2003)

"...a terrific job in this timely creation of a compilation of articles that appropriately addresses this issue." (Briefings in Bioinformatics)

From the Author

This book includes chapters from many of the leaders in the field and is intended to serve as a reference text for graduate students undertaking bioinformatics as a major or any established scientist wishing to understand the field at a time when biological structure is key to our understanding of living systems. --This text refers to an out of print or unavailable edition of this title.

Inside This Book (Learn More)
First Sentence
The precise definition of bioinformatics is a matter of some debate. Read the first page
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Concordance
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Front Cover | Copyright | Table of Contents | Excerpt | Index | Back Cover
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Most helpful customer reviews
5.0 out of 5 stars Terrific Book Oct. 17 2003
By A Customer
Format:Hardcover
"...a terrific job in this timely creation of a compilation of articles that appropriately addresses this issue." (Briefings in Bioinformatics)
Was this review helpful to you?
5.0 out of 5 stars Recommended Book July 24 2003
By A Customer
Format:Paperback
"...recommended for anyone who wishes to develop bioinformatics tools for protein structure analysis." (The Biotech Journal, April/May 2003)
Was this review helpful to you?
5.0 out of 5 stars Useful and Timely Sept. 3 2003
By A Customer
Format:Paperback
"...a useful and timely summary of a rapidly expanding field." (Nature Structural Biology, Vol. 10, No. 8, August 2003)
Was this review helpful to you?
Most Helpful Customer Reviews on Amazon.com (beta)
Amazon.com: 5.0 out of 5 stars  4 reviews
7 of 9 people found the following review helpful
5.0 out of 5 stars A Legit review from a REAL: reader June 16 2006
By Pete Gramp - Published on Amazon.com
Format:Paperback
Ok, there are 3 reviews listed here from what seems to be the authors or their closest friends... I give these about as much credit as whale dung at the bottom of the ocean. That being said, this *IS* an awesome summation of current knowledge in the fields of Structural biology and bioinformatics, especially for one with a working (undergraduate) knowledge of biological building blocks.

A few things of note: the book is aimed at biologists. This is not to imply that computer scientists or actuarial scientists will never understand this book, but rather implies that the approach to instruction is taken from the biological realm and then expanded to other related fields.

Also note that this is aimed strictly at comparative structural bioinformatics. While mentioned in the book, topics like transcription factors, x-ray crystalographic methods, or multi-cell signalling networks are best left for other books. This particular book, while touching on the subjects, does not go into much depth in these subjects. Personally, I feel this is all the better, allowing for a better primer of the subjects.

All in all, I have to say that this is one of the best books to date for an upper-undergraduate / graduate student to gain a working knowledge of Structural Bioinformatics. As such, I gladly rate this a 5 star book!
2 of 23 people found the following review helpful
5.0 out of 5 stars Useful and Timely Sept. 3 2003
By A Customer - Published on Amazon.com
Format:Paperback
"...a useful and timely summary of a rapidly expanding field." (Nature Structural Biology, Vol. 10, No. 8, August 2003)
3 of 26 people found the following review helpful
5.0 out of 5 stars Recommended Book July 24 2003
By A Customer - Published on Amazon.com
Format:Paperback
"...recommended for anyone who wishes to develop bioinformatics tools for protein structure analysis." (The Biotech Journal, April/May 2003)
0 of 18 people found the following review helpful
5.0 out of 5 stars Terrific Book Oct. 17 2003
By A Customer - Published on Amazon.com
Format:Hardcover
"...a terrific job in this timely creation of a compilation of articles that appropriately addresses this issue." (Briefings in Bioinformatics)
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