We use this text (now in its 7th edition) for both our Analytical I (chemical analysis) and Analytical II (instrumental analysis) courses. They are both 1-semester courses at the sophomore year, and this text is just the correct level and length to cover both courses. There are a number of broad sections, each of which is divided into several chapters. Roughly the 1st half covers chemical methods and the second half covers the instrumental methods. There are also a few chapters devoted to statistical analysis.
The sections are reasonably independent and can be done in pretty much any order, giving a great degree of flexibility. The text itself is easy to read with numerous descriptive diagrams. I say this for second-year level courses - the text is too superficial for higher levels. There is a good mix of descriptive chemistry to give the student a feel for the chemistry behind the analyses. Finally, there are adequate exercises at the end of the chapters, some of which are cumulative with previous sections. There is also a very handy tutorial on the use of Microsoft's Excel for use in a course like this, including some specific exercises in using the spreadsheet. I find it very helpful, and not at all exclusive for those using Excel since Quatro-Pro (and Lotus?) is very similar and contains help files that translate from Excel parlance.
My biggest issue is lack of a section on mass spectroscopy. Skoog's own "Instrumental Analysis" text has a fine section on mass spec, but this text contains virtually no mention of the technique, in spite of the fact that it is an increasingly important technique for both quantitative and qualitative trace analysis. However, that's the only real negative point - this text is very good and useful for 2nd year level analytical courses. (P.S. students find it straightforward and clear as well.)