Among the topics Asimov writes about in this work are: The Fossil Fuels, Recipe for an Ocean, Technology and Energy, The Glorious Sun, The Large Satellites of Jupiter, Of Life Beyond, The Beginning and the End, Gravitation Unlimited, Man and Computer, The Big Weather Change,America A.D.2176, The Coming Decades in Space, Colonizing the Heavens, the Moon as Threshold.
Here is a bit of the kind of speculation the book is rich in. These are the concluding words of the title essay of this volume.
"Can we allow ourselves to wonder whether everything that exists is one of an infinite number of such objects that arises out of something more fundamental than itself, which is, in turn ,one of an infinite number of such objects that arises out of something still more fundamental which is itself one of an infinite number of such objects that-
And so on, and on, and so on-
Without beginning, and without end."