The novel The Eclipse Blues is a tale of reverse power and fortune that comes about in the United States thirty years into the 21st Century as a result of massive global warming that's referred to by scientist as "the global warming mega-effect". As a result of the "global warming mega-effect" many diseases such as tuberculosis, the West Nile virus, and malaria are widely manifested. The most extensive debilitating disease is metastasis skin cancer that grows into a pandemic and greatly impacts and destroys the lives of people with pale and fair complexions - mostly Caucasians - who, as a result, become gravely ill and suffer a high mortality rate that subsequently makes them the minority in the United States to people of color who discriminate against them and prompt Caucasians to fight for their civil rights and equal justice much like people of color did during previous decades. Two influential personalities, Lutheran Minister Jerry Hines and newspaper owner Dewey Washington, come to the forefront in the story as protagonists who work diligently to end discrimination, inequality, and injustice toward pale-skinned citizens. These men put a lot on the line, including their own well-being, and in the case of Washington, the life of his daughter who is kidnapped by deranged David Butterfield, who is the diabolic leader of the Pale-skinned People Warriors Party that has declared vengeance and therewith violence against people of color.