An avalanche has delayed a trans-European train in a nameless village in an eastern European country some time before World War II. In this village there is chaos due to the sudden over crowding, which leads to a shortage of hotel rooms where visitors meet new people. At the end of the night someone is murdered under peculiar circumstances, however, the murder remains unknown to the people in the village. In the morning of the very next day someone pushes a pot that happens to land on the head of Iris Henderson (Margaret Lockwood), and she suffers from lightheadedness. A polite old lady, that Iris met the night before due to a disturbing musician, offers to help her on board the train and to take care of her. When Iris wakes up at a later occasion it seems like the old lady has vanished, and no one seems to know who she was. She desperately seeks aid from the very same musician, Gilbert Redman (Michael Redgrave), who disturbed her sleep the previous night. These two characters set out to find out what has happened to the lost lady. Lady Vanishes is a quick humorous thriller that offers both deep belly laughs as well as exhilarating suspense. There are moments where the humor turns to slap-stick humor that seems to go overboard, yet it balances well with the daft lead of Iris. In the end, the combination between the absurd and the serious provides a clever satire that offers an exceptional cinematic experience.