I really wanted to like this book. I totally believe in the Paleo way of eating and living, but it feels as though Wolf pushed this to print before it was really ready. I will try to be fair and as balanced as I can be.
I enjoyed the information on digestion and the science behind the metabolism of grains, fats, etc. Most of this I already knew, but Wolf had a good approach to the material that offered me some new information. I also found good information on exercise and why it was crucial. I enjoyed the science in these chapters; Wolf has obviously done his homework and was willing to share it, here.
However, several times I was frustrated because he refers to things he "covers later" and never talks about again. There is no index, either, so finding information afterwards is very difficult. After explaining why grains were a bad idea for the body, he mentions that dairy should be avoided, too, but he does not do the work to explain why, which I found sloppy on his part.
The tone of the book could be considered 'fun', I guess, if you don't mind being treated like a silly girl ("Buttercup") who doesn't know much and has no desire to learn anything more. I like to do research and use my brain, though, so I admit I was annoyed at times with his writing style.
The section on physical training could have been better organized; the material could be offered more clearly for those who have not worked out with weights before. It focuses quite well on those who have been sedentary, which I thought was good, but these people may have lots of questions afterwards.
In short, there was some good information here but I think there was more work to do on this book before it went to press. Hopefully a newer edition will be born from this effort. I would suggest Mark Sisson's Primal Blueprint for a very thorough and informative take on the Paleo lifestyle.