I'm a 25-year-old female comics fan, and I've been impressed with the "Minx" line [I've read "Re-Gifters", "Kimmie66", "Confessions of a Blabbermouth", "Good as Lily", and "Clubbing"]. I was really looking forward to "The Plain Janes", given my previous enjoyment of the rest of the line. I was sadly mistaken.
The biggest issue with "The Plain Janes" is that every character who is not the central character is completely one-dimensional. All of the adults are cardboard cut-outs who scream, freak out, and are otherwise completely unreasonable. The other students each have one particular trait [sporty, nerdy, theater geek, gay, good-looking, popular] and that's about it. Even the main character isn't terribly well-rounded, as all she seems to do is freak out, not freak out, and talk about how awesome it is that she's brought art to the obviously lacking suburb which she lives.
The pseudo-9/11 plot does nothing for this book except drag it down. It's overused to the point of being boring, and all it does is set up a couple of ridiculous scenes where Jane's mother yells at her, and then Jane acts surprised when she's grounded for sneaking out of the house and hitchhiking nine hours to check on a John Doe she writes to at the hospital.
This book needed a better writer. Mike Carey, who wrote "Confessions of a Blabbermouth" and "Re-Gifters" should have been given this book. He writes teenagers much more realistically than Cecil Castellucci and does so in a way that doesn't make the adults come off as horrible, useless things that are just out to stop the teenagers from having a good time.
Read the rest of the "Minx" line, or buy it for the teenage girl in your life, but let this one rot on the shelf.