From my point of view, "Ugly Betty" is the kind of tv series that can make a fan out of you instantly, even if you watch just an episode. So if you don't have some free time you can dedicate to it every week, remember to avoid this show like the plague :)
Why is this series fun? It's about a young girl from Queens, Betty (America Ferrera), that begins to work as assistant to Daniel (Eric Mabius), the new editor-in-chief at a fashion magazine. Betty is very intelligent and kind, but has a characteristic that amounts to sin in the world of fashion: she is not beautiful. The different episodes show us how she copes with stereotypes, makes new friends, finds love and tries to fight off the people who don't like her or want to see her boss fail.
I think that you will be surprised by how good the actors in "Ugly Betty" are (even though special mention should be given to America Ferrara and Vanessa Williams, everybody shines). But more importantly, I believe that you will love the fact that a show that entertains also happens to deliver a strong and positive message. This tv series allows us to watch things that we take for granted from an unjaundiced point of view, that is from Betty's perspective, saying things that need to be said, but in such a way that you end up being entertained, and wanting to know what will happen next week. And then, you are hooked :)
All in all, a show to recommend...