- You'll save an extra 5% on Books purchased from Amazon.ca, now through July 29th. No code necessary, discount applied at checkout. Here's how (restrictions apply)
The Cutter Incident: How Americas First Polio Vaccine Led to the Growing Vaccine Crisis Paperback – Sep 28 2007
Special Offers and Product Promotions
No Kindle device required. Download one of the Free Kindle apps to start reading Kindle books on your smartphone, tablet, and computer.
Getting the download link through email is temporarily not available. Please check back later.
To get the free app, enter your mobile phone number.
From Publishers Weekly
After a wave of books celebrating the 50th anniversary of Jonas Salk's polio vaccine, Offit's troubling account is the first to focus on a largely forgotten aspect—one with negative repercussions 50 years later. In a nuanced examination of a complex story, Offit, a professor of pediatrics and expert in infectious diseases, relates how Cutter Laboratories, one of several pharmaceutical companies licensed to produce Salk's killed-virus vaccine, shipped many lots of vaccine containing live virus, creating a mini polio epidemic: 40,000 children became ill, 200 were permanently paralyzed, 10 died. Offit carefully examines how Cutter was and was not responsible: tests for detecting live virus at the time were simply not sensitive enough, but Cutter departed from Salk's safe production protocols. And while the company knew there was a problem, it failed to notify the government's oversight agency. Cutter faced costly lawsuits that have resulted, according to Offit, in today's vaccine crisis: shortages (think of last year's flu vaccine) due to pharmaceutical companies' unwillingness to risk testing and producing vaccines and face possible litigation. In another example of the law of unintended consequences, Offit shows how "the Cutter Incident" led Salk's vaccine to be replaced by a less safe one: Sabin's live-virus vaccine. (Oct.)
Copyright © Reed Business Information, a division of Reed Elsevier Inc. All rights reserved. --This text refers to an out of print or unavailable edition of this title.
Pointing to recent shortages of flu and several childhood-disease vaccines as well as the dearth of new vaccines, Offit says that pharmaceutical companies are staying away from vaccine research and production in droves. He lays responsibility for this lamentable situation on the outcome of a court battle now 50 years old and the subsequent snowballing of legal and legislative reactions. Beginning with a tragic 1955 error at Cutter Laboratories--one of the first companies producing the Salk polio vaccine--that caused polio in thousands, Offit maps the way the courts have handled pharmaceutical liability, the way juries have awarded damages, the federal Vaccines for Children Program and the National Vaccine Injury Compensation Program, and other influences on vaccine development. Those trends and agencies have so inflated the costs and risks relative to probable profits that vaccine production has been discouraged. Offit concludes that, because the U.S. has made risks high and profits negligible, many more children will suffer illnesses that can be prevented. Donna Chavez
Copyright © American Library Association. All rights reserved --This text refers to an out of print or unavailable edition of this title.
Most Helpful Customer Reviews on Amazon.com (beta)
1955 was still the dawn of the vaccine era, and there was much to be learned. However, in the aftermath of the vaccine, liability law was changed in a way that seemed minor at the time, but has resulted in a dearth of vaccines and vaccine makers. Do you want to know why 2004 witnessed a shortage of flu vaccines? Read this book and find out!
Overall, I must say that I found this book to be quite fascinating. The author does a good job of retelling what happened, and what its ramifications were and are. It seems quite ironic that something that went wrong at the dawn of vaccines is bringing the era of vaccines to a close! If you want to know how we got from that seemingly glorious era of ever new vaccines, which seemed to promise a disease free future, to day, then you must read this book. I highly recommend it!
Most significantly, this is an excellent book both for biologists with a strong background in microbiology, etc, and for laypeople. I gave this book to my mother, a civil engineer by training who hasn't studied biology since high school, and she enjoyed it greatly as well.
I strongly recommend this to anyone interested in biology, public health, epidemiology, and science literacy, as well as for scientists looking for gifts for their non-scientist loved ones.
Look for similar items by category
- Books > History > Americas > United States > 20th Century
- Books > History > United States > 20th Century
- Books > Medical Books > Administration & Medicine Economics > Public Health
- Books > Medical Books > History
- Books > Medical Books > Medicine > Preventive Medicine
- Books > Science & Math > History & Philosophy > History of Medicine
- Books > Science & Math > Medicine > Administration & Policy > Public Health
- Books > Science & Math > Medicine > Physician & Patient > Medical Ethics
- Books > Science & Math > Medicine > Specialties > Preventive Medicine