- Paperback: 448 pages
- Publisher: St. Martin's Griffin; Reprint edition (Oct. 14 2008)
- Language: English
- ISBN-10: 0312367074
- ISBN-13: 978-0312367077
- Product Dimensions: 15.7 x 3.1 x 23.6 cm
- Shipping Weight: 612 g
- Average Customer Review: 3 customer reviews
- Amazon Bestsellers Rank: #139,717 in Books (See Top 100 in Books)
Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime Paperback – Oct 14 2008
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“(Dr.) de Grey is hardly just another fountain-of-youth huckster. His it-might-work ideas are based on existing, published, peer-reviewed research. He thinks more like an engineer than a scientist. If even one of his proposals works, it could mean years of extended healthy living.” ―Paul Boutin, The Wall Street Journal
About the Author
Aubrey de Grey, Ph.D., is chairman and chief science officer of the Methuselah Foundation, and editor-in-chief of Rejuvenation Research, the only peer-reviewed academic journal focusing on intervention in aging. He has formulated a wide-ranging plan for the comprehensive and eventually indefinite postponement of age-related physical and mental decline, named SENS (Strategies for Engineered Negligible Senescence). He is the organizer of an ongoing series of conferences and workshops that focus on the key biomedical research relevant to SENS, and he also oversees the Methuselah Foundation's growing sponsorship of SENS research worldwide.
Michael Rae is Dr. de Grey's research assistant. He is a longtime member and onetime board member of the Calorie Restriction Society, a main contributor to the society's "How-to Guide," and a core scientific investigator with the society's Cohort Study, which seeks to document the feasibility of calorie restriction in humans and the potential human translatability of the anti-aging effects observed in laboratory organisms.
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Instead of trying to understand everything about metabolism or pathologies, he's focusing on repairing the damage caused by metabolism *before* it can create pathologies. It is basically the approach of repairing the roof of your house periodically to avoid catastrophic failure -- to be able to do that you don't need to understand all the causality chains that create the damage, you just need to know how to repair it.
This book has inspired me to learn about molecular biology and biochemistry. I've ordered a few textbooks. I think that this, in itself, is the highest recommendation for the book; anything that can inspire to learn more and get involved (I also donated to the Methuselah Foundation) is special. I highly recommend this book. It is well-written, easy to understand for the lay person yet detailed.
Dr. de Grey also touches on the politics of aging - the resistance many people feel because "we're all supposed to get old and die," akin to the resistance against antibiotics expressed by some religious fundamentalists, or the resistance against organ transplants and blood transfusions that pervaded when these were new medical advances. His hope is to raise scientific research funds to be used to usher in a new age of health and productivity, whereinwhich people may become injured and die or may become ill and die, but will not simply grow weak and sick because they have lived for 100 years.
The book is a fantastic read, not only because it conveys the modern medical advances of geriatrics in layman's terms, but because it is written from a forward looking optimism that gives the reader a "yes we can" point of view on the future of aging. There are children alive today who will likely see their 200th birthdays and this book turns that pie-in-the-sky statement into a logical conclusion, of course making a few assumptions about our future progress in our current research.
It's a wonderful read that I couldn't put down and have recommended to friends and family who have a penchant for light science reading, evolutionary biology, and medicine.
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thoughts and approaches towards slowing down the aging process