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Goodman and Gilman's The Pharmacological Basis of Therapeutics, Twelfth Edition Hardcover – Jan 10 2011

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Product Details

  • Hardcover: 1808 pages
  • Publisher: McGraw-Hill Education / Medical; 12 edition (Jan. 10 2011)
  • Language: English
  • ISBN-10: 0071624422
  • ISBN-13: 978-0071624428
  • Product Dimensions: 21.1 x 7 x 26.2 cm
  • Shipping Weight: 3.6 Kg
  • Average Customer Review: Be the first to review this item
  • Amazon Bestsellers Rank: #94,544 in Books (See Top 100 in Books)
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Product Description

About the Author

Laurence L. Brunton, PhD<br>Professor of Pharmacology and Medicine<br>University of California, San Diego<p>Laurence Brunton trained under Alfred Goodman-Gilman and is nationally recognized for his expertise in cell signaling and cardivacular pharmacology.  He has published more than 200 original research papers.

Bruce Chabner, MD Professor of Medicine Harvard Medical School Director, Massachusetts General Hospital Cancer Center Boston, MA

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Most Helpful Customer Reviews on Amazon.com (beta)

Amazon.com: HASH(0xa2181cc0) out of 5 stars 69 reviews
41 of 43 people found the following review helpful
HASH(0xa2c8d7d4) out of 5 stars Kindle Version of Goodman and Gilman's March 11 2012
By Book Omnivore - Published on Amazon.com
Format: Kindle Edition Verified Purchase
I have several editions of this book in hard copy since the 1970's. As ever it is very authoritative and a good reference if you have the scientific and medical background to understand it. The only problem with the Kindle version is that the tables and figures are virtually unreadable!
25 of 29 people found the following review helpful
HASH(0xa2176fc0) out of 5 stars Good reference, poor instructor. April 18 2013
By J. Tillema - Published on Amazon.com
Format: Hardcover Verified Purchase
This is probably a good desk reference for a physician, but it is a poor instructional aide, and is full of errors and omissions of important information.

This is a 2000 page book, and goes into excruciating detail to the point where the grand scheme is lost. Moreover, the excruciating detail is not well explained, or starts out well explained and abruptly digresses before the explanation's conclusion. The cardiac action potential is one such example.

As an instructional aide, it is very poor. It is very difficult to learn from this book, and some explanations are wrong. As an example, an this book describes an inverse agonist as a type of regulatory ligand that stabilizes a receptor in its inactive form, which is incorrect. It should be described as a type of regulatory ligand that reduces activity below a receptor's basal rate.

There are numerous errors in page layout that affect the way the outline of the material is perceived. As an example, in the general principles section where the physiological receptors are presented, there is a nice table showing the various types of receptors. The body of the text does not unfold as expected. I will use an outline format as an analogy. A proper presentation would unfold as such:

I. Receptors
B. ion-gated
C. nuclear receptor
D. etc
1. etc
a. etc

What we get instead is:

A. receptors
B. ion-gated
I. nuclear receptor
C. etc
1. etc.
a. etc.

The headings are completely screwed up. Nuclear receptor looks like a new section in the chapter.

Also, the book goes back and forth between regular print and microscopic print in the body of the text. And the microscopic print is smaller than image and table captions.

Finally, the index is terrible. It has many key omissions that are inexcusable for a book in its 12 edition. NMDA receptors are an important class of receptors, and it is described with illustrations in the chapter on the CNS, but NMDA receptors are nowhere to be found in the index.

The illustrations are beautiful, but are far too large, requiring the explanation to be on adjacent pages, requiring one to flip back and forth. As an aside, the high quality images are why I give this book 3/5 rather than 2/5.

So I guess it's clear that I don't like this book, and am returning it.
10 of 10 people found the following review helpful
HASH(0xa217c9c0) out of 5 stars Must have Jan. 17 2012
By pharmtoxgal - Published on Amazon.com
Format: Hardcover
I frequently utilize this text for all my academic research writing in my pharmacology & toxicology program. Overall, this resource provides the reader with the necessary detail s/he will need to know to succeed in pharmacology courses that are offered in professional schools such as pharmacy or medical school and graduate (MS/PhD) pharmacology & toxicology programs. I'm fortunate to have an outstanding prof at my university who is a contributing author in one of these sections in this book. I definitely recommend this book and I'm not just saying that because my prof is a contributing author, for I already used this book long before he became my prof.
30 of 36 people found the following review helpful
HASH(0xa232cc6c) out of 5 stars Almost perfect... Aug. 30 2011
By Amazon Customer - Published on Amazon.com
Format: Hardcover
This is indeed the go to book for medicine questions, be you pharmacist, physician, medical student, nurse, nursing student, or whatever. I have been using it for years and will continue to do so.

That being said, there is one quirk that I wish McGraw Hill would fix. With at least two editions I've owned, including the current one, there is an annoying, unexplained switch from a normal font to a very small font. The small font seems to come on without warning, and for my eyes it is very difficult to read. This morning, for example, I was reviewing digoxin. The introductory paragraphs were easy to read, but for unknown reasons the section on adverse effects (and the section following that) was in the small print. Why would you want to make something this important more difficult to read? This change to small font occurs seemingly randomly throughout the text, and is extremely aggravating.

As I age, I will continue to go to Goodman and Gilman for reference, but I hope as my eyes age future editions will eschew this exasperating practice of tiny fonts.
9 of 9 people found the following review helpful
HASH(0xa24a9bdc) out of 5 stars 12th edition versus 5th Edition: The original editors versus the new ones. May 4 2014
By Michael Moran - Published on Amazon.com
Format: Hardcover Verified Purchase
The 12th edition is a good update of many of the newer drugs on the market, however, if you want a more complete discussion of a an older drug, and earlier edition of Goodman and Gilman, (that is edited by them) often gives a more thorough and complete review. The newer edition tends to gloss over the the older drugs in favor of the newer ones. My advice to physicians: Hold on to your earlier editions.