PART I: MOLECULAR COMPONENTS OF CELLS. 1. Chemistry is the Logic of Biological Phenomena. 2. Water: The Medium of Life. 3. Thermodynamics of Biological Systems. 4. Amino Acids and Polypeptides. 5. Proteins: Secondary, Tertiary, and Quaternary Structure. 6. Lipids, Membranes, and Transport. 7. Carbohydrates and Cell Surfaces. 8. Nucleotides and Nucleic Acids. 9. Recombinant DNA: Cloning and Creation of Chimeric Genes. PART II: PROTEIN DYNAMICS. 10. Enzymes: Their Kinetics, Specificity, and Regulation. 11. Mechanisms of Enzyme Action. 12. Proteins of the Blood. 13. Molecular Motors. PART III: METABOLISM AND ITS REGULATION. 14. The Organization of Metabolism. 15. Glycolysis. 16. The Tricarboxylic Acid Cycle. 17. Electron Transport and Oxidative Phosphorylation. 18. Photosynthesis. 19. Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway. 20. Lipid Metabolism. 21. Amino Acid and Nucleotide Metabolism. 22. Metabolic Integration and Organ Specialization. PART IV: INFORMATION TRANSFER. 23. DNA: Replication, Recombination, and Repair. 24. Transcription and the Regulation of Gene Expression. 25. Protein Synthesis and Degradation. 26. Signal Transduction: The Relay of Metabolic and Environmental Information.
About the Author
Reginald H. Garrett was educated in the Baltimore city public schools and at the Johns Hopkins University, where he received his Ph.D. in biology in 1968. Since that time, he has conducted research and taught biochemistry courses at the University of Virginia, where he is currently Professor of Biology. He is the author of numerous papers and review articles on biochemical, genetic, and molecular biological aspects of inorganic nitrogen metabolism. His early research focused on the pathway of nitrate assimilation in filamentous fungi. His investigations contributed substantially to our understanding of the enzymology, genetics, and regulation of this major pathway of biological nitrogen acquisition. More recently, he has collaborated in systems approaches to the metabolic basis of nutrition-related diseases. His research has been supported by grants from the National Institutes of Health, the National Science Foundation, and private industry. A member of the American Society for Biochemistry and Molecular Biology, Garrett is a former Fulbright Scholar, was twice Visiting Scholar at the University of Cambridge, and was Invited Professor at the University of Toulouse, France.